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The Stuttgart midfielder rose to nod the ball beyond Fernando Muslera after Uruguay failed to clear a late corner, while Diego Forlan was inches away from a dramatic equaliser with an injury-time free-kick that struck the crossbar.
Forlan rounded off an impressive individual showing at the tournament with a brilliantly-taken volley to give Uruguay a 2-1 lead early in the second period, only for Marcell Jansen to restore parity moments later.